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123. Social responsiveness and psychosis-risk: a multi-perspective approach
Social deficits are widely characterized as central to psychosis and may play a particularly relevant role in the developmental sensitive prodromal stage, a time when adolescents and young adults are building the skills that will set the pace and stage for the rest of a lifetime. However, to date, our understanding of social dysfunction has relied primarily on specific experimental paradigms or entirely on global functioning scales. To move forward with developing better treatments (targeted to the individual) or better markers of risk progression, understanding 1) domains of social dysfunction, and 2) perspectives through which these types of dysfunctions are happening are critical.
The current study addresses the concept of social responsiveness, a critical component of social functioning that encompasses reciprocal social behavior in children. Specifically, we will focus on awareness, motivation, communication, cognition, and mannerism domains and aim to determine which areas are impacted in youth at clinical high-risk for psychosis (CHR). Next, we will evaluate correlates of between affected domains, and conceptually relevant symptoms that are common in those with psychosis risk syndromes. Notably, this study will employ a range of different assessment, across parent report, clinical observation, and participant behavior to provide a more comprehensive perceptive.